Pathophysiology and prevention of postoperative peritoneal adhesions
نویسندگان
چکیده
منابع مشابه
Pathophysiology and prevention of postoperative peritoneal adhesions.
Peritoneal adhesions represent an important clinical challenge in gastrointestinal surgery. Peritoneal adhesions are a consequence of peritoneal irritation by infection or surgical trauma, and may be considered as the pathological part of healing following any peritoneal injury, particularly due to abdominal surgery. The balance between fibrin deposition and degradation is critical in determini...
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Objective(s): Abdominal adhesions are one of the most important problems, occurring after intra-abdominal surgery in more than 90% of cases. This condition is the leading cause of bowel obstruction, infertility, and abdominal/pelvic pain. Gold nanoparticles (GNPs) have been shown to be non-toxic and exhibit anti-inflammatory, anti-angiogenic and antioxidant activities. The purpose of this study...
متن کامل[Prevention of postoperative adhesions].
Postoperative adhesions represent a common consequence in patients who underwent abdominal or pelvic surgery. Such adhesions can be asymptomatic, but they can cause complications such as chronic abdomino-pelvic pain, secondary infertility, an increase in bowel obstruction risk and more complexity for future surgery, including longer surgery times and an increase in morbidity. Normally, adhesion...
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The fact that adhesions can form following abdominal surgery has been known since the beginning of surgery. Yet during the early years of surgery, adhesion formation received little attention, the focus being on infection and survival. In the seventies clinical endocrinology developed explosively, driven by the introduction of oral contraceptives and by the introduction of radioimmunoassays—a t...
متن کاملRole of the peritoneal cavity in the prevention of postoperative adhesions, pain, and fatigue.
A surgical trauma results within minutes in exudation, platelets, and fibrin deposition. Within hours, the denuded area is covered by tissue repair cells/macrophages, starting a cascade of events. Epithelial repair starts on day 1 and is terminated by day 3. If repair is delayed by decreased fibrinolysis, local inflammation, or factors in peritoneal fluid, fibroblast growth starting on day 3 an...
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ژورنال
عنوان ژورنال: World Journal of Gastroenterology
سال: 2011
ISSN: 1007-9327
DOI: 10.3748/wjg.v17.i41.4545